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HOPE for Harvey
Home
Harvey's Story
Leadership
Donate Today!
Treatment
Events/Blog
More
  • Home
  • Harvey's Story
  • Leadership
  • Donate Today!
  • Treatment
  • Events/Blog
  • Home
  • Harvey's Story
  • Leadership
  • Donate Today!
  • Treatment
  • Events/Blog

Welcome to the HOPE for Harvey Foundation for DLG4

Welcome to the HOPE for Harvey Foundation for DLG4Welcome to the HOPE for Harvey Foundation for DLG4Welcome to the HOPE for Harvey Foundation for DLG4

Helping Overcome PSD-95 Errors for the DLG4 Community

Donate Today!

Welcome to the HOPE for Harvey Foundation for DLG4

Welcome to the HOPE for Harvey Foundation for DLG4Welcome to the HOPE for Harvey Foundation for DLG4Welcome to the HOPE for Harvey Foundation for DLG4

Helping Overcome PSD-95 Errors for the DLG4 Community

Donate Today!

Help us Finish our mRNA Treatment by Summer 2026

Jackson Labs has successfully designed and bred a Harvey DLG4 mouse and starting in mid-November 2025, Grann Pharma will begin testing a Lipid Nano Particle (LNP) mRNA-based treatment, which will send good copies of DLG4 into the body through regular infusions on our Harvey mouse.  This LNP mRNA treatment is showing amazing and safe results in another active clinical trial in just 18 months.  We hope to submit our pre-Investigational New Drug application to the FDA by the end of 2025, finalize our safety studies by spring 2026, submit our final IND FDA application by spring 2026 with hopes to start our first clinical trial for an Investigational New DLG4 Drug in Austin, TX by summer 2026!  

You can help make this possible by donating today!  

Help us raise the last $190,000 we need to complete those safety studies.

Beginnings of HOPE for Harvey

Our Mission

To further research and create translational medicine and treatment options that create a better quality of life for DLG4 patients. 


In the long-term we hope our efforts will go beyond DLG4 and help increase research and legislation in this field for early detection and treatment of all rare genetic disorders.

25MM+

Only 5%

25MM+

Americans affected by rare genetic diseases like DLG4

10K+

Only 5%

25MM+

identified

genetic disorders

Only 5%

Only 5%

Only 5%

of disorders have an FDA-approved treatment

Harvey's Story

In March of 2020, we gave birth to our second child, Harvey. At 18-months, he was diagnosed with DLG4-related Synaptopathy. Harvey is now 5-years-old, and struggles with seizures, independent mobility and cannot speak or feed himself.  He has difficulty learning due to a random, single letter mutation on the DLG4 gene

Read more

Give HOPE

We hope to be in clinical trials for a Lipid Nano Particle mRNA treatment by summer 2026!  

Help make that possible for Harvey and DLG4!

There's still hope.  Donate today!

100% of donations go straight to researchers

Donate Now

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